The importance of input sequence set to consensus-derived proteins and their relationship to reconstructed ancestral proteins.

Nixon, Charlotte; Lim, Shion A; Sternke, Matt; Barrick, Doug; Harms, Mike; Marqusee, Susan

Nixon, Charlotte; Lim, Shion A; Sternke, Matt; Barrick, Doug; Harms, Mike; Marqusee, Susan.

Afiliação

Nixon C; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720.
Lim SA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720.
Sternke M; The T.C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218.
Barrick D; The T.C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218.
Harms M; Department of Chemistry and Biochemistry, University of Oregon, Eugene, OR 97403.
Marqusee S; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720.

bioRxiv ; 2023 Jul 01.

Article em En | MEDLINE | ID: mdl-37425932

Palavras-chave

Ancestral Sequence Reconstruction; Consensus Design; Protein Folding; Protein Stability; Singular Value Decomposition

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article País de publicação: Estados Unidos

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