Amino acids contribute to adaptive thermogenesis. New insights into the mechanisms of action of recent drugs for metabolic disorders are emerging.

Ruocco, Chiara; Malavazos, Alexis Elias; Ragni, Maurizio; Carruba, Michele O; Valerio, Alessandra; Iacobellis, Gianluca; Nisoli, Enzo

Ruocco, Chiara; Malavazos, Alexis Elias; Ragni, Maurizio; Carruba, Michele O; Valerio, Alessandra; Iacobellis, Gianluca; Nisoli, Enzo.

Afiliação

Ruocco C; Center for Study and Research on Obesity, Department of Biomedical Technology and Translational Medicine, University of Milan, via Vanvitelli, 32, 20129 Milan, Italy.
Malavazos AE; Endocrinology Unit, Clinical Nutrition and Cardiovascular Prevention Service, IRCCS Policlinico San Donato, Piazza Edmondo Malan, 2, San Donato Milanese, 20097 Milan, Italy; Department of Biomedical, Surgical and Dental Sciences, University of Milan, via della Commenda, 10, 20122 Milan, Italy.
Ragni M; Center for Study and Research on Obesity, Department of Biomedical Technology and Translational Medicine, University of Milan, via Vanvitelli, 32, 20129 Milan, Italy.
Carruba MO; Center for Study and Research on Obesity, Department of Biomedical Technology and Translational Medicine, University of Milan, via Vanvitelli, 32, 20129 Milan, Italy.
Valerio A; Department of Molecular and Translational Medicine, University of Brescia, viale Europa, 11, 25123 Brescia, Italy.
Iacobellis G; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Miami, 1400 NW 12th Ave, Miami, FL, USA.
Nisoli E; Center for Study and Research on Obesity, Department of Biomedical Technology and Translational Medicine, University of Milan, via Vanvitelli, 32, 20129 Milan, Italy. Electronic address: enzo.nisoli@unimi.it.

Pharmacol Res ; 195: 106892, 2023 09.

Article em En | MEDLINE | ID: mdl-37619907

Assuntos

Aminoácidos; Doenças Metabólicas; Animais; Humanos; Termogênese; Tecido Adiposo Marrom; Adipocinas

Palavras-chave

Adaptive thermogenesis; Adipose autophagy; Branched-chain amino acids; Brown adipose tissue; Dual agonists; Obesity; Secretome; Uncoupling protein 1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aminoácidos / Doenças Metabólicas Limite: Animals / Humans Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália País de publicação: Holanda

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