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Pharmacokinetic study of Tdp1 inhibitor resulted in a significant increase in antitumor effect in the treatment of Lewis lung carcinoma in mice by its combination with topotecan.
Okhina, Alina A; Kornienko, Tatyana E; Rogachev, Artem D; Luzina, Olga A; Popova, Nelly A; Nikolin, Valery P; Zakharenko, Alexandra L; Dyrkheeva, Nadezhda S; Pokrovsky, Andrey G; Salakhutdinov, Nariman F; Lavrik, Olga I.
Afiliação
  • Okhina AA; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of Russian Academy of Sciences, Lavrent'ev ave., 9, Novosibirsk 630090, Russia; Novosibirsk State University, Pirogov St., 2, Novosibirsk 630090, Russia.
  • Kornienko TE; Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of Russian Academy of Sciences, Lavrent'ev ave., 8, Novosibirsk 630090, Russia.
  • Rogachev AD; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of Russian Academy of Sciences, Lavrent'ev ave., 9, Novosibirsk 630090, Russia; Novosibirsk State University, Pirogov St., 2, Novosibirsk 630090, Russia.
  • Luzina OA; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of Russian Academy of Sciences, Lavrent'ev ave., 9, Novosibirsk 630090, Russia.
  • Popova NA; Novosibirsk State University, Pirogov St., 2, Novosibirsk 630090, Russia; Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 10, Novosibirsk 630090, Russia.
  • Nikolin VP; Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 10, Novosibirsk 630090, Russia.
  • Zakharenko AL; Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of Russian Academy of Sciences, Lavrent'ev ave., 8, Novosibirsk 630090, Russia.
  • Dyrkheeva NS; Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of Russian Academy of Sciences, Lavrent'ev ave., 8, Novosibirsk 630090, Russia.
  • Pokrovsky AG; Novosibirsk State University, Pirogov St., 2, Novosibirsk 630090, Russia.
  • Salakhutdinov NF; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of Russian Academy of Sciences, Lavrent'ev ave., 9, Novosibirsk 630090, Russia.
  • Lavrik OI; Novosibirsk State University, Pirogov St., 2, Novosibirsk 630090, Russia; Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of Russian Academy of Sciences, Lavrent'ev ave., 8, Novosibirsk 630090, Russia. Electronic address: lavrik@niboch.nsc.ru.
J Pharm Biomed Anal ; 236: 115731, 2023 Nov 30.
Article em En | MEDLINE | ID: mdl-37741072
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Pharm Biomed Anal Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Federação Russa País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Pharm Biomed Anal Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Federação Russa País de publicação: Reino Unido