Quantitation and characterization of glucosylsphingosine in cerebrospinal fluid (CSF), plasma, and brain of monkey model with Gaucher disease.

Sato, Sho; Matsumoto, Shin-Ichi; Kosugi, Yohei

Sato, Sho; Matsumoto, Shin-Ichi; Kosugi, Yohei.

Afiliação

Sato S; Drug Metabolism & Pharmacokinetics Research Laboratories, Preclinical & Translational Sciences, Research, Takeda Pharmaceutical Company Limited, Shonan Health Innovation Park, 26-1, Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa, 251-8555, Japan. Electronic address: sho.sato@takeda.com.
Matsumoto SI; Drug Metabolism & Pharmacokinetics Research Laboratories, Preclinical & Translational Sciences, Research, Takeda Pharmaceutical Company Limited, Shonan Health Innovation Park, 26-1, Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa, 251-8555, Japan.
Kosugi Y; Drug Metabolism & Pharmacokinetics Research Laboratories, Preclinical & Translational Sciences, Research, Takeda Pharmaceutical Company Limited, Shonan Health Innovation Park, 26-1, Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa, 251-8555, Japan.

Drug Metab Pharmacokinet ; 53: 100530, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37924723

Assuntos

Doença de Gaucher; Animais; Humanos; Doença de Gaucher/genética; Psicosina/análise; Cromatografia Líquida; Espectrometria de Massas em Tandem; Encéfalo

Palavras-chave

Cerebrospinal fluid; Conduritol-ß-epoxide; GBA; Gaucher disease; Glucocerebrosidase; Glucosylsphingosine; Parkinson's disease

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Gaucher Limite: Animals / Humans Idioma: En Revista: Drug Metab Pharmacokinet Assunto da revista: FARMACOLOGIA / METABOLISMO Ano de publicação: 2023 Tipo de documento: Article País de publicação: Reino Unido

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