Anti-Inflammatory Activity of 1,6,7-Trihydroxy-2-(1,1-dimethyl-2-propenyl)-3-methoxyxanthone Isolated from <i>Cudrania tricuspidata</i> via NF-&#954;B, MAPK, and HO-1 Signaling Pathways in Lipopolysaccharide-Stimulated RAW 264.7 and BV2 Cells.

Ko, Wonmin; Baek, Jong-Suep; Liu, Zhiming; Dong, Linsha; Kim, Nayeon; Lee, Hwan; Yoon, Chi-Su; Kim, Na Young; Kim, Sam Cheol; Lee, Dong-Sung

Anti-Inflammatory Activity of 1,6,7-Trihydroxy-2-(1,1-dimethyl-2-propenyl)-3-methoxyxanthone Isolated from Cudrania tricuspidata via NF-κB, MAPK, and HO-1 Signaling Pathways in Lipopolysaccharide-Stimulated RAW 264.7 and BV2 Cells.

Ko, Wonmin; Baek, Jong-Suep; Liu, Zhiming; Dong, Linsha; Kim, Nayeon; Lee, Hwan; Yoon, Chi-Su; Kim, Na Young; Kim, Sam Cheol; Lee, Dong-Sung.

Afiliação

Ko W; College of Pharmacy, Wonkwang University, 460, Iksan-daero, Iksan-si 54538, Republic of Korea.
Baek JS; Department of Bio-Health Convergence, Kangwon National University, 1, Kangwondaehak-gil, Chuncheon-si 24341, Republic of Korea.
Liu Z; College of Pharmacy, Chosun University, 309, Pilmun-daero, Dong-gu, Gwangju 61452, Republic of Korea.
Dong L; College of Pharmacy, Chosun University, 309, Pilmun-daero, Dong-gu, Gwangju 61452, Republic of Korea.
Kim N; College of Pharmacy, Chosun University, 309, Pilmun-daero, Dong-gu, Gwangju 61452, Republic of Korea.
Lee H; College of Pharmacy, Chosun University, 309, Pilmun-daero, Dong-gu, Gwangju 61452, Republic of Korea.
Yoon CS; College of Pharmacy, Wonkwang University, 460, Iksan-daero, Iksan-si 54538, Republic of Korea.
Kim NY; Pathology Division, National Institute of Fisheries Science, 216, Gijanghaean-ro, Gijang-eup, Gijang-gun, Busan 46083, Republic of Korea.
Kim SC; Department of Family Practice and Community Medicine, Chosun University College of Medicine, 309, Pilmun-daero, Dong-gu, Gwangju 61452, Republic of Korea.
Lee DS; College of Pharmacy, Chosun University, 309, Pilmun-daero, Dong-gu, Gwangju 61452, Republic of Korea.

Molecules ; 28(21)2023 Oct 27.

Article em En | MEDLINE | ID: mdl-37959718

Assuntos

Moraceae; NF-kappa B; NF-kappa B/metabolismo; Proteínas Quinases Ativadas por Mitógeno/metabolismo; Lipopolissacarídeos/farmacologia; Anti-Inflamatórios/farmacologia; Anti-Inflamatórios/metabolismo; Transdução de Sinais; Microglia/metabolismo; Interleucina-6/metabolismo; Dor/metabolismo; Óxido Nítrico/metabolismo; Óxido Nítrico Sintase Tipo II/metabolismo; Ciclo-Oxigenase 2/metabolismo

Palavras-chave

1,6,7-Trihydroxy-2-(1,1-dimethyl-2-propenyl)-3-methoxyxanthone; mouse macrophage RAW 264.7; mouse microglia BV2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: NF-kappa B / Moraceae Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de publicação: Suíça

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