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MCC950 reduces autophagy and improves cognitive function by inhibiting NLRP3-dependent neuroinflammation in a rat model of Alzheimer's disease.
Naeem, Abdul; Prakash, Ravi; Kumari, Neha; Ali Khan, Mohsin; Quaiyoom Khan, Abdul; Uddin, Shahab; Verma, Sandeep; Ab Robertson, Avril; Boltze, Johannes; Shadab Raza, Syed.
Afiliação
  • Naeem A; Laboratory for Stem Cell & Restorative Neurology, Department of Biotechnology, Era's Lucknow Medical College & Hospital, Era University, Sarfarazganj, Lucknow 226003, India.
  • Prakash R; Laboratory for Stem Cell & Restorative Neurology, Department of Biotechnology, Era's Lucknow Medical College & Hospital, Era University, Sarfarazganj, Lucknow 226003, India.
  • Kumari N; Laboratory for Stem Cell & Restorative Neurology, Department of Biotechnology, Era's Lucknow Medical College & Hospital, Era University, Sarfarazganj, Lucknow 226003, India.
  • Ali Khan M; Era University, Sarfarazganj, Lucknow 226003, India.
  • Quaiyoom Khan A; Translational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
  • Uddin S; Translational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
  • Verma S; Department of Chemistry, Indian Institute of Technology, Kanpur, UP 208016, India.
  • Ab Robertson A; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
  • Boltze J; School of Life Sciences, University of Warwick, Coventry, UK.
  • Shadab Raza S; Laboratory for Stem Cell & Restorative Neurology, Department of Biotechnology, Era's Lucknow Medical College & Hospital, Era University, Sarfarazganj, Lucknow 226003, India; Department of Stem Cell Biology and Regenerative Medicine, Era's Lucknow Medical College & Hospital, Era Universit
Brain Behav Immun ; 116: 70-84, 2024 02.
Article em En | MEDLINE | ID: mdl-38040385

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Proteína 3 que Contém Domínio de Pirina da Família NLR Limite: Aged / Animals / Humans Idioma: En Revista: Brain Behav Immun Assunto da revista: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Índia País de publicação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Proteína 3 que Contém Domínio de Pirina da Família NLR Limite: Aged / Animals / Humans Idioma: En Revista: Brain Behav Immun Assunto da revista: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Índia País de publicação: Holanda