Fatty Oil of Descurainia Sophia Nanoparticles Improve Monocrotaline-Induced Pulmonary Hypertension in Rats Through PLC/IP3R/Ca<sup>2+</sup> Signaling Pathway.

Zheng, Yajuan; Yuan, Peipei; Zhang, Zhenkai; Fu, Yang; Li, Saifei; Ruan, Yuan; Li, Panying; Chen, Yi; Feng, Weisheng; Zheng, Xiaoke

Fatty Oil of Descurainia Sophia Nanoparticles Improve Monocrotaline-Induced Pulmonary Hypertension in Rats Through PLC/IP3R/Ca²⁺ Signaling Pathway.

Zheng, Yajuan; Yuan, Peipei; Zhang, Zhenkai; Fu, Yang; Li, Saifei; Ruan, Yuan; Li, Panying; Chen, Yi; Feng, Weisheng; Zheng, Xiaoke.

Afiliação

Zheng Y; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, People's Republic of China.
Yuan P; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, People's Republic of China.
Zhang Z; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou, 450046, People's Republic of China.
Fu Y; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, People's Republic of China.
Li S; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, People's Republic of China.
Ruan Y; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou, 450046, People's Republic of China.
Li P; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, People's Republic of China.
Chen Y; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, People's Republic of China.
Feng W; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, People's Republic of China.
Zheng X; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450008, People's Republic of China.

Int J Nanomedicine ; 18: 7483-7503, 2023.

Article em En | MEDLINE | ID: mdl-38090366

Assuntos

Hipertensão Pulmonar; Nanopartículas; Ratos; Animais; Hipertensão Pulmonar/induzido quimicamente; Hipertensão Pulmonar/tratamento farmacológico; Hipertensão Pulmonar/metabolismo; Ratos Sprague-Dawley; Monocrotalina/efeitos adversos; Fosfolipases Tipo C/efeitos adversos; Fosfolipases Tipo C/metabolismo; Artéria Pulmonar; Transdução de Sinais

Palavras-chave

PLC/IP3R/Ca2+; RPASMC; fatty oil; nanoparticles; pulmonary hypertension

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanopartículas / Hipertensão Pulmonar Limite: Animals Idioma: En Revista: Int J Nanomedicine Ano de publicação: 2023 Tipo de documento: Article País de publicação: Nova Zelândia

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