Incidence, factors, and prognostic analyses of challenging cardiopulmonary bypass separation in Chinese cardiac surgical populations.
Minerva Anestesiol
; 90(3): 144-153, 2024 03.
Article
em En
| MEDLINE
| ID: mdl-38127467
ABSTRACT
BACKGROUND:
Challenging separation from cardiopulmonary bypass (CPB) has been associated with multiple medical adversities, while its incidence, associated factors, and prognosis among cardiac surgery populations are substantially understudied.METHODS:
Adult cardiac surgical patients in two medical centers were retrospectively analyzed. Separation from CPB was stratiï¬ed as easy, difï¬cult, or complex, based on the use of pharmacologic assistance agents and mechanical supports. The various in-hospital adverse outcomes (e.g., mortality, common complications) were assessed.RESULTS:
The incidence of difficult and complex separation from CPB was 21.9% (1159 cases, 95% CI 20.8% to 23.1%), and 6.1% (320 cases, 95% CI 5.4% to 6.7%), respectively. High age, the presence of pulmonary hypertension or unstable angina, decreased ejection fraction, and emergency surgery were more frequently associated with challenging separation from CPB. Patients who experienced challenging separation from CPB had an elevated risk of adverse outcomes, including in-hospital mortality (complex odds ratio [OR] 2.85), composite infection events (difficult OR=1.82; complex OR=1.88), major adverse cardiac events (difficult OR=1.40; complex OR=1.57), pulmonary complications (difficult OR=1.31; complex OR=1.20), acute kidney injury (difficult OR=1.75; complex OR=2.64), and prolonged postoperative hospital stays.CONCLUSIONS:
We depicted the incidence of challenging separation from CPB among cardiac surgery population. Additionally, results of influential factors and various adverse outcome analyses emphasize the potential of interventions aimed at preventing difficult or complex separation from CPB and reducing associated adverse outcomes.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ponte Cardiopulmonar
/
Procedimentos Cirúrgicos Cardíacos
Limite:
Adult
/
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Minerva Anestesiol
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China
País de publicação:
IT
/
ITALIA
/
ITALY
/
ITÁLIA