Intramolecular Cobalt/Visible Light Cocatalyzed Reductive Coupling of Unactivated Arenes with Unactivated Alkenes.
Org Lett
; 26(1): 327-331, 2024 Jan 12.
Article
em En
| MEDLINE
| ID: mdl-38160449
ABSTRACT
A protocol for the intramolecular reductive coupling of unactivated arenes with unactivated alkenes has been developed with the aid of a cooperative visible light/cobalt catalytic system. This coupling is achieved via radical cascade cyclization using amines as terminal reducing reagents and water as the main hydrogen source. In their form, readily available N-allyl benzamides are converted to the corresponding spiro cyclohexadiene-lactam or ß-phenethylamine analogues in moderate to excellent yields.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Org Lett
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China
País de publicação:
Estados Unidos