SLC25A39 links mitochondrial GSH sensing with iron metabolism.

Chen, Xiong; Gan, Boyi

Chen, Xiong; Gan, Boyi.

Afiliação

Chen X; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Gan B; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; The University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA. Electronic address: bgan@mdanderson.org.

Mol Cell ; 84(4): 616-618, 2024 Feb 15.

Article em En | MEDLINE | ID: mdl-38364779

ABSTRACT

ABSTRACT

Two recent studies by Liu et al.1 in Science and Shi et al.2 in this issue of Molecular Cell identify a mitochondrial GSH-sensing mechanism that couples SLC25A39-mediated GSH import to iron metabolism, advancing our understanding of nutrient sensing within organelles.

Assuntos

Ferro; Mitocôndrias; Proteínas de Transporte da Membrana Mitocondrial; Glutationa/metabolismo; Ferro/metabolismo; Mitocôndrias/genética; Mitocôndrias/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte da Membrana Mitocondrial / Ferro / Mitocôndrias Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

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