Neurobiological mechanisms and therapeutic impact of electroconvulsive therapy (ECT).
Rom J Morphol Embryol
; 65(1): 13-17, 2024.
Article
em En
| MEDLINE
| ID: mdl-38527979
ABSTRACT
Electroconvulsive therapy (ECT) is an efficient therapeutic resource for psycho-pharmacotherapeutic resistant forms of depression. ECT is a form of electrical brain stimulation involving the induction of a controlled seizure, clinically similar to an epileptic seizure, that is initiated in the prefrontal region of the brain and spreads to the cortex and subcortex, including the diencephalic structures. This is achieved by creating a transcranial electric field and synchronously depolarizing neuronal membranes. The mechanisms of action of ECT are not yet fully understood, but several hypotheses have been proposed to explain how it affects the brain neurotransmitter changes, neuroplasticity, network connectivity, endocrine system regulation and changes in regional cerebral blood flow and regional metabolism.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Eletroconvulsoterapia
Limite:
Humans
Idioma:
En
Revista:
Rom J Morphol Embryol
Assunto da revista:
ANATOMIA
/
EMBRIOLOGIA
Ano de publicação:
2024
Tipo de documento:
Article
País de publicação:
RO
/
ROMANIA
/
ROMÊNIA
/
RUMANIA