Predicting Preterm Birth Using Proteomics.
Clin Perinatol
; 51(2): 391-409, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38705648
ABSTRACT
The complexity of preterm birth (PTB), both spontaneous and medically indicated, and its various etiologies and associated risk factors pose a significant challenge for developing tools to accurately predict risk. This review focuses on the discovery of proteomics signatures that might be useful for predicting spontaneous PTB or preeclampsia, which often results in PTB. We describe methods for proteomics analyses, proteomics biomarker candidates that have so far been identified, obstacles for discovering biomarkers that are sufficiently accurate for clinical use, and the derivation of composite signatures including clinical parameters to increase predictive power.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Biomarcadores
/
Proteômica
/
Nascimento Prematuro
Limite:
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
Clin Perinatol
Ano de publicação:
2024
Tipo de documento:
Article
País de publicação:
Estados Unidos