Effects of topical insulin on second-degree burn wound healing: brief report.
Wound Manag Prev
; 70(2)2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38959345
ABSTRACT
BACKGROUND:
Burns are classified according to their mechanism of injury, depth, affected body area, affected region or part of the body, and extent of the lesions. Topical insulin modulates the healing process. However, studies evaluating the effects of topical insulin treatment on burns in human patients are lacking.PURPOSE:
The purpose of this study was to investigate the effects of topical insulin on healing time of second-degree burns.METHODS:
In this nonrandomized clinical trial, patients with second-degree burns were allocated to a control group (CG) or an intervention group (IG) in which wounds were treated with 1% silver sulfadiazine and topical insulin, respectively.RESULTS:
Healing time was significantly shorter in the IG relative to the CG (9.1 ± 1.9 days and 12.7 ± 3.3 days, respectively; P < .05). The estimated burn area was similar in both groups (CG 1.44 ± 1.0%; IG 1.42 ± 0.53%).CONCLUSION:
In this study, topical insulin reduced healing time in second-degree burns. Further investigation is warranted to support wider use in clinical practice.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cicatrização
/
Queimaduras
/
Administração Tópica
/
Insulina
Limite:
Adult
/
Female
/
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Wound Manag Prev
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA