Reducing residual chlortetracycline in wastewater using a whole-cell biocatalyst.
Ecotoxicol Environ Saf
; 282: 116717, 2024 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-39002381
ABSTRACT
Antibiotic contamination has become an increasingly important environmental problem as a potentially hazardous emergent and recalcitrant pollutant that poses threats to human health. In this study, manganese peroxidase displayed on the outer membrane of Escherichia coli as a whole-cell biocatalyst (E. coli MnP) was expected to degrade antibiotics. The manganese peroxidase activity of the whole-cell biocatalyst was 13.88 ± 0.25â¯U/L. The typical tetracycline antibiotic chlortetracycline was used to analyze the degradation process. Chlortetracycline at 50â¯mg/L was effectively transformed via the whole-cell biocatalyst within 18â¯h. After six repeated batch reactions, the whole-cell biocatalyst retained 87.2â¯% of the initial activity and retained over 87.46â¯% of the initial enzyme activity after storage at 25°C for 40 days. Chlortetracycline could be effectively removed from pharmaceutical and livestock wastewater by the whole-cell biocatalyst. Thus, efficient whole-cell biocatalysts are effective alternatives for degrading recalcitrant antibiotics and have potential applications in treating environmental antibiotic contamination.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poluentes Químicos da Água
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Clortetraciclina
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Escherichia coli
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Águas Residuárias
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Antibacterianos
Idioma:
En
Revista:
Ecotoxicol Environ Saf
Ano de publicação:
2024
Tipo de documento:
Article
País de publicação:
Holanda