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Advances in Psoriatic Disease Research: Insights From GRAPPA Pilot Research Awardees.
Elliott, Ashley; Gill, Tejpal; Kim, Jaehwan; Shutova, Maria S; FitzGerald, Oliver; Pennington, Stephen R; Rooney, Madeleine; Deodhar, Atul; Raychaudhuri, Siba P; Boehncke, Wolf-Henning; de Vlam, Kurt; Chandran, Vinod; Liao, Wilson.
Afiliação
  • Elliott A; A. Elliott, MB Bch BAO, MSc, PhD, Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
  • Gill T; T. Gill, PhD, Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, Oregon, USA.
  • Kim J; J. Kim, MD, PhD, Department of Dermatology, University of California Davis, Davis, California, and Dermatology Section, Veterans Affairs Northern California Health Care System, Mather, California, and Laboratory for Investigative Dermatology, the Rockefeller University, New York, New York, USA.
  • Shutova MS; M.S. Shutova, PhD, University of Geneva, Department of Pathology and Immunology, and University Hospitals of Geneva, Division of Dermatology and Venereology, Geneva, Switzerland.
  • FitzGerald O; O. FitzGerald, MD, School of Medicine, UCD Conway Institute for Biomolecular Research, University College Dublin, Dublin, Ireland.
  • Pennington SR; S.R. Pennington, PhD, School of Medicine, UCD Conway Institute for Biomolecular Research, University College Dublin, Dublin, Ireland.
  • Rooney M; M. Rooney, MD, Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
  • Deodhar A; A. Deodhar, MD, Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, Oregon, USA.
  • Raychaudhuri SP; S.P. Raychaudhuri, MD, Department of Dermatology and Rheumatology, University of California Davis, Davis, and Dermatology and Rheumatology Section, Veterans Affairs Northern California Health Care System, Mather, California, USA.
  • Boehncke WH; W.H. Boehncke, MD, University of Geneva, Department of Pathology and Immunology, and University Hospitals of Geneva, Division of Dermatology and Venereology, Geneva, Switzerland.
  • de Vlam K; K. de Vlam, MD, PhD, Department of Rheumatology, University Hospital, and Department of Development and Regeneration, Skeletal Biology and Engineering Research Center, KU Leuven, Leuven, Belgium.
  • Chandran V; V. Chandran, DM, PhD, Departments of Medicine, Laboratory Medicine and Pathobiology and Institute of Medical Science, University of Toronto, and Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
  • Liao W; W. Liao, MD, Department of Dermatology, University of California San Francisco, San Francisco, California, USA.
J Rheumatol ; 2024 Jul 15.
Article em En | MEDLINE | ID: mdl-39009398
ABSTRACT
Research progress from the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) pilot award program was presented and discussed at the GRAPPA 2023 annual meeting. Topics included identification of protein biomarkers associated with enthesitis in psoriatic arthritis (PsA), the role of HLA-B27 on gut microbial dysbiosis in PsA, single-cell profiling of synovial fluid vs psoriatic skin lesions in PsA, and the role of mechanotransduction in hyperactivation of transforming growth factor-ß via αVß6 integrin in psoriatic epidermis.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Rheumatol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Rheumatol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Reino Unido