[Genotype and phenotype of apolipoprotein E in patients with Alzheimer's disease in Castille and Leon]. / Genotipo y fenotipo de la apolipoproteína E en enfermos de Alzheimer en Castilla y León.
Neurologia
; 12(9): 384-8, 1997 Nov.
Article
em Es
| MEDLINE
| ID: mdl-9471175
ABSTRACT
We determined the variants of the apolipoprotein E (apo-E) in a sample taken from a castellano-leonesa population with Alzheimer's disease (AD). The prevalence of the allele E-4 is 0.33 in AD and 0.12 in the control group. This results allow us to estimate that the risk of suffering from the disease is higher when the patients have an allele E-4. A significant correlation was found between the presence of the allele E4 and the AD (p < 0.005).
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Apolipoproteínas E
/
Doença de Alzheimer
Tipo de estudo:
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Es
Revista:
Neurologia
Assunto da revista:
NEUROLOGIA
Ano de publicação:
1997
Tipo de documento:
Article