Urea production and salvage during pregnancy in normal Jamaica women
Am J Clin Nutr
; 60(3): 341-6, Sept. 1994.
Artigo
| MedCarib
| ID: med-10776
Biblioteca responsável:
JM3.1
Localização: JM3.1; RC620.A1A4
ABSTRACT
The pattern of aggregated nitrogen demand during pregnancy and the fetal and maternal components are unclear. Excess demand enhances efficiency of nitrogen utilization. Urea salvage contributes to enhanced efficiency. Dietary protein intake, urea production, and salvage of urea nitrogen were measured in eight nonpregnant control subjects, and trimesterly in nine pregnant women. Production was measured after prime-intermittent intravenous doses of [15N15N]-urea by dilution of label in urinary urea. Dietary protein intake was greater in trimester 1 than in nonpregnant women (167 ñ 36 vs 224 ñ 60 mg N.kg-1.d-1), and increased further in trimester 2 (266 ñ 59 mg N.kg-1.d-1). Urea production was not higher during pregnancy. Despite higher protein intake urea salvage was higer in pregnancy (40 ñ 24 nonpregnant vs 77 ñ 23, 61 ñ 31, and 51 ñ 12 mg N.kg-1.d-1). Therefore, the demand-supply gap for nitrogen was greatest early in pregnancy when fetoplacental growth is slowest, and implies heightened maternal demand (AU)
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Coleções:
Bases de dados internacionais
Base de dados:
MedCarib
Assunto principal:
Ureia
/
Gravidez
/
Proteínas na Dieta
/
Nitrogênio
Tipo de estudo:
Estudo observacional
Limite:
Adulto
/
Feminino
/
Humanos
País/Região como assunto:
Caribe Inglês
/
Jamaica
Revista:
Am J Clin Nutr
Ano de publicação:
1994
Tipo de documento:
Artigo