Glucose tolerance and insulin sensitivity in malnourished children
Br J Nutr;27(May): 585-92, 1972.
em Inglês
| MedCarib
| ID: med-10848
Biblioteca responsável:
JM3.1
Localização: JM9.1; QP141.A1B7
ABSTRACT
In malnourished, compared with recovered children, fasting blood glucose concentrations were low and there was impared peripheral glycolysis as shown by a failure of blood lactate to raise after glucose was injected intravenously. Homogenates of muscle biopsies from malnourished and recovered children produced equal amounts of lactate when incubated anaerobically with various substrates, but when compared with homogenates of biopsies from normal children the pattern suggested an impairment of glycolysis. The rate of glucose disappearance after intravenous glucose was slow in the malnourished child and there was possibly diminished sensitivity to exogenous insulin. Isocaloric diets relatively high or low in fat were fed to children who had recovered from malnutrition. Glucose tolerance, insulin sensitivity, fasting plasma insulin and insulin response to intravenous glucose were all the same in children on either diet. (AU)
Buscar no Google
Coleções:
Bases de dados internacionais
Base de dados:
MedCarib
Assunto principal:
Glicemia
/
Teste de Tolerância a Glucose
/
Insulina
/
Distúrbios Nutricionais
Tipo de estudo:
Estudo diagnóstico
Limite:
Criança
/
Humanos
Idioma:
Inglês
Revista:
Br J Nutr
Ano de publicação:
1972