A comparison of fasting plasma insulin and growth hormone concentrations in marasmic, kwashiorkor, marasmic-kwashiorkor and underweight children
Pediatr Res
; 11(5): 637-40, 1977.
Artigo
em Inglês
| MedCarib
| ID: med-12062
Biblioteca responsável:
JM3.1
Localização: JM3.1; Reprint Collection
ABSTRACT
Fasting plasma insulin and growth hormone concentrations were measured in 24 marasmic, 11 kwashiorkor, 16 marasmic-kwashiorkor, and 4 underweight children. Hormone measurements were made by a special modification of the Hales and Randle double antibody immunoassay with increased sensitivity in the concentration range 0-25 æU/ml. Fasting plasma insulin was low in marasmus, kwashiorkor, and marasmic-kwashiorkor children, and increased to normal levels after recovery. Fasting plasma growth hormone was elevated in all groups during nutrition and was significantly decreased to normal levels after recovery. There were no significant differences in plasma insulin or growth hormone levels between the different clinical types of severe protein malnutrition. These hormonal changes in severe protein energy malnutrition are of complex and not fully understood etiology. However, recovered children appear to have a hormonal pattern similar to that described in normal control infants and children. (Summary)
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Base de dados:
MedCarib
Assunto principal:
Hormônio do Crescimento
/
Kwashiorkor
/
Desnutrição Proteico-Calórica
/
Insulina
Limite:
Humanos
/
Lactente
Idioma:
Inglês
Revista:
Pediatr Res
Ano de publicação:
1977
Tipo de documento:
Artigo