Antibodies to cardiolipin and beta2-glycoprotein-1 in HTLV-1-associated myelopathy/tropical spastic paraparesis
Lupus
; 8(3): 210-4, 1999.
Article
em En
| MedCarib
| ID: med-1306
Biblioteca responsável:
JM3.1
Localização: JM3.1;
ABSTRACT
Anticardiolipin and anti-beta2GP1 antibodies were measured in 50 patients with HTLV-1-associated Myelopathy-Tropical Spastic Paraparesis (HAM-TSP) and the results were compared with those obtained for 34 HTLV-1-positive and 35 HTLV-1-negative controls, as well as 128 SLE patients. aCL but not anti-beta2GP1 was associated with HTLV-I infection. aCL was more prevalent than anti-beta2GP1 (32 percent vs. 8 percent) and was not associated with anti-beta2GP1 in HAM-TSP. IgA was the dominant isotype of aCL and anti-beta2GP1. The data suggest that tin HAM-TSP, IgA aCL are frequent and are associated with HTLV-1 infection.(Au)
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Coleções:
01-internacional
Base de dados:
MedCarib
Assunto principal:
Glicoproteínas
/
Paraparesia Espástica Tropical
/
Anticorpos Antifosfolipídeos
/
Anticorpos Anticardiolipina
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Lupus
Ano de publicação:
1999
Tipo de documento:
Article