Vitamin A and zinc supplementation of preschool children
J Am Coll Nutr
; 18(3): 213-22, Jun. 1999.
Artigo
em Inglês
| MedCarib
| ID: med-1348
Biblioteca responsável:
JM3.1
Localização: JM3.1;
ABSTRACT
OBJECTIVE:
To determine whether supplementation of vitamin A and/or zinc (Zn) improved serum levels of these nutrients and/or height and weight gains in preschool children, 22 to 66 months, living in Belize, Central America.METHODS:
Subjects received either Zn, vitamin A, Zn and vitamin A or a placebo (70 mg Zn and/or 3030 RE vitamin A, once per week) for 6 months in a 2x2 factorial design. Forty-three children, from a population of 104 prescreened, completed the study; they were selected, prior to treatment, for low/marginal serum concentrations of these micronutrients.RESULTS:
Serum Zn levels were greater (16 percent, p < 0.001) for those who received Zn. In contrast, after vitamin A treatment, there were no differences in serum vitamin A among groups. Although increases in height (+4.4 cm, p<0.001) and weight (+0.79 kg, p<0.001), compared with baseline values, were numerically greatest for children who received both supplements, only the vitamin A supplementation effect was significant, resulting in increased height (+1.4 cm, p<0.002) and greater weight gain (+0.15 kg, p<0.03) compared to those receiving no vitamin A. Vitamin A supplementation alone significantly increased (p<0.001) hemoglobin concentration.CONCLUSION:
The results suggest that the preschool children in this study, prescreened for low/marginal serum concentrations from a larger population prior to treatment, were enduring inadequate vitamin A and, to a lesser degree, Zn nutriture. Height and weight gain were significantly increased in the subjects who received a single weekly supplement 3030 RE of vitamin A.(Au)
Buscar no Google
Coleções:
Bases de dados internacionais
Base de dados:
MedCarib
Assunto principal:
Vitamina A
/
Zinco
/
Estatura
/
Peso Corporal
/
Suplementos Nutricionais
Tipo de estudo:
Ensaio clínico controlado
Limite:
Criança
/
Criança, pré-escolar
/
Humanos
País/Região como assunto:
América Central
/
El Salvador
Idioma:
Inglês
Revista:
J Am Coll Nutr
Ano de publicação:
1999
Tipo de documento:
Artigo