Thyroid-Gonad relationship in systemic lupus erythematosus
West Indian med. j
; 40(3): 124-6, Sept. 1991.
Artigo
em Inglês
| MedCarib
| ID: med-13605
Biblioteca responsável:
JM3.1
Localização: JM3.1; R18.W4
ABSTRACT
Thirty women with systemic lupus erythematosus (SLE) were examined to assess the thyroid-gonad relationship. Significant decreases in mean serum tri-iodo-thyronine and testerone levels and increases in mean serum estradiol and luteinizing hormone levels were observed in SLE patients as compared to control subjects. The serum levels of thyroxine, thyrotropin, tri-iodo-thyronine uptake, free thyroxine index and prolactin were, however, not significantly different in both groups. The interpretation of these findings is unclear but SLE could be regarded as one of the nonthyroidal systematic illness since low serum tri-iodo-thyrotropin levels were observed in our patients. Furthermore, high levels of estradiol and low levels of testosterone in our female patients may indicate involvement of sex steroids in the pathogenesis of SLE. (AU)
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Coleções:
Bases de dados internacionais
Base de dados:
MedCarib
Assunto principal:
Hipófise
/
Hormônios Esteroides Gonadais
/
Glândula Tireoide
/
Lúpus Eritematoso Sistêmico
Tipo de estudo:
Estudo de etiologia
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
West Indian med. j
Ano de publicação:
1991
Tipo de documento:
Artigo