The excretion of 5-oxoproline in urine, as an index of glycine status, during normal pregnancy
Br J Obstet Gynaecol
; 96: 440-4, Apr. 1989.
Artigo
em Inglês
| MedCarib
| ID: med-14628
Biblioteca responsável:
JM3.1
Localização: JM3.1; Reprint collection / JM3.1; RG1.B7
ABSTRACT
The urinary excretion of 5-oxoproline, which may be used as an index of glycine status, was investigated in 30 normal pregnant women during different stages of pregnancy and in 18 non-pregnant female volunteers. During an 18-h study there was little variation in the 5-oxoproline/creatinine index,and a single sample gave a representative value. The excretion of 5-oxoproline/creatinine (umol/mmol) rose progressively as preqnancy advanced (non-pregnant mean 10, SD 5, first trimester mean 46, SD 12, second trimester mean 150, SD 180,and third trimester mean 280, SD 320) and by the third trimester was over 20 times greater than in non-pregnant women. The data suggest that as pregnancy advances the endogenous production of glycine may be insufficient to satisfy the increasing demands (Summary)
Buscar no Google
Coleções:
Bases de dados internacionais
Base de dados:
MedCarib
Assunto principal:
Ácido Pirrolidonocarboxílico
/
Gravidez
/
Glicina
Limite:
Humanos
/
Gravidez
Idioma:
Inglês
Revista:
Br J Obstet Gynaecol
Ano de publicação:
1989
Tipo de documento:
Artigo