Evaluation of Trinidad and Tobago traditional medicine I: effects of traditional folk remedy on diarrhoea
Journal of the Caribbean Veterinary Medical Association
; 1(2): 13-7, July 2001. ilus, tab
Artigo
em Inglês
| MedCarib
| ID: med-16860
Biblioteca responsável:
TT5
Localização: TT5; W1 JO920C
ABSTRACT
Hot aqueous extract of bark of Anacardium occidentale (Cashew), commonly used in Trinidadian folk medicine for the treatment of diarrhoea was evaluated for antidiarrhoeal activity. The extract inhibited castor oil-induced diarrhoea in rats as judged by a decrease in the number of wet faeces in the extract-treated rats. The extract was also inhibited the propulsive movement of intestinal contents in mice. The extract showed no direct effect on the isolated guinea-pig ileum, however, it inhibited in a dose-related manner the contractile effects of acetylcholine, histamine, and 5-hydroxytryptamine. The inhibitary effects on these agonists were non competitive in nature. Phytochemical tests revealed the main constituents as tannin, steroids, triterpenoid and carbohydrates. The results indicates that action of A. occidentale bark extract could be through a combination of inhibition of elevated transmitter released and reduced propulsive movement of the small intestine. There is merit in the folk medicinal use of the extract (AU)
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Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
Doenças Negligenciadas
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
Diarreia
/
Doenças Negligenciadas
Base de dados:
MedCarib
Assunto principal:
Trinidad e Tobago
/
Terapias Complementares
/
Anacardium
/
Diarreia
/
Antidiarreicos
Limite:
Animais
País/Região como assunto:
Caribe Inglês
/
Trinidad e Tobago
Idioma:
Inglês
Revista:
Journal of the Caribbean Veterinary Medical Association
Ano de publicação:
2001
Tipo de documento:
Artigo