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The effect of malnutrition on the pattern of growth in the rat kidney and the renal response to acidosis
Br J Nutr ; 31(2): 113, 1974.
Artigo em Inglês | MedCarib | ID: med-5060
Biblioteca responsável: JM3.1
Localização: JM9.1; QP141.A1B7
ABSTRACT
The kidneys of normal rats were analysed for water, fat, protein, RNA and DNA, at 10, 21 and 36 d after birth. The effects on growth caused by two types of malnutrition were investigated. An increase in the RNADNA ratio was demonstrated between 10 and 36 d, contrary to previous evidence that this ratio is fixed at birth. Energy deficiency during the first 21 d of life resulted mainly in fewer kidney cells, whereas protein-energy deficiency between 21 and 36 d reulted mainly in a smaller cellular content of RNA and protein. In response to metabolic acidosi, both groups of malnourished rats increased urinary excretion of ammonia and there was enhanced gluconeogenesis in vitro; the basal rate of gluconeogenesis was lower in the protein-energy-deficient rats than in the controls. Protein-energy-deficient rats did not exhibit the renal hypertrophy shown by the control rats in response to acidosis (AU)
Assuntos
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Coleções: Bases de dados internacionais Base de dados: MedCarib Assunto principal: Acidose / Rim / Distúrbios Nutricionais Limite: Animais Idioma: Inglês Revista: Br J Nutr Ano de publicação: 1974 Tipo de documento: Artigo
Buscar no Google
Coleções: Bases de dados internacionais Base de dados: MedCarib Assunto principal: Acidose / Rim / Distúrbios Nutricionais Limite: Animais Idioma: Inglês Revista: Br J Nutr Ano de publicação: 1974 Tipo de documento: Artigo
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