Some characteristics of Trinidad and Tobago kidney stone formers - abstract

ABSTRACT

During the period June 1983 to June 1985, 79 kidney stone formers of Trinidad and Tobago were evaluated by the ambulatory protocol of Pak, and their acid loading and urine citrate levels measured. Patient receiving medications that could affect the metabolism of calcium, uric acid or oxalate were asked to discontinue their use before and throughout the period of evalution. Forty-five males and 34 females were examined. Mean age of males was 43 years and of females 43 years. Males passed 3.4 ñ 4.4 stones in the previous 3 years and retained 1.0 ñ 2.2 stones. Females passed 1.9 ñ 2.7 stones in the previous 3 years and retained 1.7 ñ 2.9. Mean 24 hr urine volumes were as follows females 1,464 ñ 786 ml; Males 1,369 ñ 585 ml. Renal hypercalciuria was found in three, absorptiive hyperuricosuria in one and hyperparathyroidism in one person. One person had renal tubular acidosis; seven had hyperuricosuria. Ten persons had high urine calcium levels because of a high dietary calcium intake. Hypocitraturia was found in 38 out of 50 respondents examined. A metabolic abnormality was found in 77 percent of the patients (AU)