Your browser doesn't support javascript.
loading
The selection of chemical markers in faeces for the identification of geophagia - abstract
West Indian med. j ; 41(Suppl 1): 68, Apr. 1992.
Artigo em Inglês | MedCarib | ID: med-6516
Biblioteca responsável: JM3.1
Localização: JM3.1; R18.W4
ABSTRACT
Geophagia is the deliberate ingestion of soil and has been associated with geohelminthiasis, lead poisoning and other conditions of public health importance. It seems worthwhile therefore to investigate the extent of geophagia in the general population. One approach to the identification and quantification of geophagia would be to detect in faeces naturally occurring soil-specific chemical markers. These markers should exist in low concentration in food, water and other edibles, be of low bioactivity, and be excreted quantitatively in faeces. This study reports the selection of chemical markers common to Jamaican soils to be used as indicators of geophagia in the general population. Three common Jamaica soils were sterilised and placed in 1g gelatin capsules. Five volunteers were each asked to ingest 10 g of one of the soils with carmine (an inert gastrointestinal dye). A pre-ingestion faecal sample and all post-ingestion faecal samples were collected until no more carmine was seen in the faeces. The procedures was repeated for the other two soils. All faecal and soil samples were examined by Instrumental Neutron Activation Analysis (INAA). A total of 14 elements were found to be common to the three soils used in this study. Of these, dysprosium, europium, cerium, hafnium and thorium wer consistently detected in the post-ingestion faecals but not in the preingestion faecals. These five elements should make excellent markers of geophagia as they are present in insignificant levels in good compared to soil and seem to have low bioactivity. INAA has the highest sensitivity for dysprosium and europium and both have short processing time (30 minutes per sample). INAA and the use of dysprosium and/or europium as chemical markers would appear to be a promising basis for the detection of geophagia in the general population (AU)
Assuntos
Buscar no Google
Coleções: Bases de dados internacionais Base de dados: MedCarib Assunto principal: Biomarcadores Tipo de estudo: Estudo diagnóstico / Estudo prognóstico País/Região como assunto: Caribe Inglês / Jamaica Idioma: Inglês Revista: West Indian med. j Ano de publicação: 1992 Tipo de documento: Artigo / Congresso e conferência
Buscar no Google
Coleções: Bases de dados internacionais Base de dados: MedCarib Assunto principal: Biomarcadores Tipo de estudo: Estudo diagnóstico / Estudo prognóstico País/Região como assunto: Caribe Inglês / Jamaica Idioma: Inglês Revista: West Indian med. j Ano de publicação: 1992 Tipo de documento: Artigo / Congresso e conferência
...