Intradermal immunization against Asian influenza (abstract only)

ABSTRACT

Influenza virus undergoes continuous antigenic alterations which at times become so profound that the antigens in the available vaccines can not protect against newly emerging variants. Such a state of affairs makes it difficult if not impossible to furnish effective vaccines in adequate amounts during outbreaks caused by such variants. When vaccine is in short supply, one asks the question about the efficacy of reduced dosages. The present report relates information which shows that using proper spacing of injections, even small amounts of antigens, may engender antibody response in various age groups, including children (AU)