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Seroprevalence of autoantibodies in selected and unselected populations in Jamaica
West Indian med. j ; 43(2): 59-62, June 1994.
Artigo em Inglês | MedCarib | ID: med-7996
Biblioteca responsável: JM3.1
Localização: JM3.1; R18.W4
ABSTRACT
Various serological techniques were used to investigate the prevalence and distribution of autoantibodies in healthy Jamaicans and patients with autoimmune and non-autoimmune disease. Low concentrations of autoantibodies were found in healthy Jamaicans, including thyroid (1.5 percent), gastric parietal cell (1.4 percent) and smooth muscle (11.3 percent). There was no significant age or sex predominance in the distribution of autoantibodies in the healthy population though autoimmune disease was more prevalent in females. Serological overlaps occurred but the comparative distributions and concentrations of autoantibodies in patients with autoimmune disease and non-autoimmune disease, and health subjects indicate that currently available methods of autoantibody determination may be used successfully in diagnosis in Jamaica. Failure to detect circulating pancreatic islet cell antibodies in insulin-dependent diabetic patients as well as in healthy Jamaicans questions the pathogenicity of these antibodies and diminished their diagnostic usefulness in this population. (AU)
Assuntos
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Coleções: Bases de dados internacionais Base de dados: MedCarib Assunto principal: Autoanticorpos / Doenças Autoimunes Tipo de estudo: Estudo diagnóstico / Fatores de risco Limite: Adolescente / Adulto / Idoso / Feminino / Humanos / Masculino País/Região como assunto: Caribe Inglês / Jamaica Idioma: Inglês Revista: West Indian med. j Ano de publicação: 1994 Tipo de documento: Artigo
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Coleções: Bases de dados internacionais Base de dados: MedCarib Assunto principal: Autoanticorpos / Doenças Autoimunes Tipo de estudo: Estudo diagnóstico / Fatores de risco Limite: Adolescente / Adulto / Idoso / Feminino / Humanos / Masculino País/Região como assunto: Caribe Inglês / Jamaica Idioma: Inglês Revista: West Indian med. j Ano de publicação: 1994 Tipo de documento: Artigo
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