Congenital yellow fever virus infection after immunization in pregnancy
J Infect Dis
; 168(6): 1520-3, Dec. 1993.
Article
em En
| MedCarib
| ID: med-8336
Biblioteca responsável:
JM3.1
Localização: JM3.1; R11.J71
ABSTRACT
To determine whether yellow fever (YF) vaccine administered in pregnancy causes fetal infection, women who were vaccinated during unrecognized pregnancy in a mass campaign in Trinidad were studied retrospectively. Maternal and cord or infant blood were tested for IgM and neutralizing antibodies to YF virus, indicating congenital infection. The infant, the first repotred case of YF virus infection after immunization in prgnancy, was delivered after an uncomplicated full-term pregnancy and appeared normal. Congenital dengue 1 infection may have occurred in another case. The frequency of fetal infection and adverse events after such exposure could not be estimated; however, the neurotropism of YF virus for the developing nervous system and the now documented possibility of trans-placental infection underscores the admonition that YF vaccination in pregnancy should be avoided (AU)
Buscar no Google
Coleções:
01-internacional
Base de dados:
MedCarib
Assunto principal:
Febre Amarela
/
Vacinas Virais
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Newborn
/
Pregnancy
País/Região como assunto:
Caribe ingles
/
Trinidad y tobago
Idioma:
En
Revista:
J Infect Dis
Ano de publicação:
1993
Tipo de documento:
Article