Comparative observations of mucus transport velocity in health and disease
Respiration
; 44(3): 184-8, May.-June 1983.
Artigo
em Inglês
| MedCarib
| ID: med-8704
Biblioteca responsável:
JM3.1
ABSTRACT
The present study evaluated mucus transport velocity (MTV) in different areas of the tracheobronchial tree in vitro in normal, acute and chronic bronchitic animals. The average MTV in animals ranged from 11.5 mm/min in the trachea to 0.64 mm/min in the pre-terminal bronchus. Chronic bronchitic animals showed mucus hypersecretion, areas of ciliary abnormality and mucus stagnation. The mean transport velocities ranged from 21.2 mm/min in the trachea to 4.1 mm/min in the pre-terminal bronchus. In the acutely ill animals, MTV ranged from 2.5 mm/min in the trachea to zero below the upper lobar bronchus. It is postulated that the higher than normal values in chronic bronchitis are due to altered mucus rheology, increased peristalsis and linear acceleration; whereas those in acute bronchitis were attributed to an early phase of viral or bacterial infection. (AU)
Buscar no Google
Coleções:
Bases de dados internacionais
Base de dados:
MedCarib
Assunto principal:
Traqueia
/
Brônquios
/
Bronquite
/
Muco
Limite:
Animais
Idioma:
Inglês
Revista:
Respiration
Ano de publicação:
1983
Tipo de documento:
Artigo