Direct determination of luminal diameter changes in intrapulmonary airways
Respiration
; 38(2): 57-64, 1979.
Artigo
em Inglês
| MedCarib
| ID: med-8764
Biblioteca responsável:
JM3.1
ABSTRACT
A method is decribed for the direct measurement of changes in luminal diameter at all levels of the airway. Using this method it was found that (i) abrupt bronchiolar collapse occurred in the preterminal and terminal bronchioles once the luminal diameter was reduced to a critical level (ii) decreased temperatures resulted in airway narrowing which was reversed by increasing the temperature to above 25 degrees C; as a rule, airway narrowing followed a cranial to caudal direction, and higher concentration of a drug being required to close the peripheral airways; (iii) bronchodilators except Carbuterol had no effect on resting bronchial tone or on acetylcholine-induced constriction in the absence of O-adrenoreceptor blockade; (iv) at 35 degrees C rhythmic waves (frequency 6--20/min) were observed; these waves travelled from the periphery in a cranial direction. (AU)
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Base de dados:
MedCarib
Assunto principal:
Brônquios
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Músculo Liso
/
Tono Muscular
Limite:
Animais
Idioma:
Inglês
Revista:
Respiration
Ano de publicação:
1979
Tipo de documento:
Artigo