Hb F Kingston (G gamma 55 (D6) Met leads to Arg)
FEBS lett
; 150(1): 77-80, Dec 13, 1982.
Artigo
em Inglês
| MedCarib
| ID: med-9338
Biblioteca responsável:
JM3.1
Localização: JM3.1; Reprint Collection
ABSTRACT
A fetal haemoglobin variant was noted in a healthy Jamaican infant of mixed African/Chinese extration. A two-dimensional chromatogram of the soluble tryptic peptides (Tp) showed 2 'new' ones. One was composed of the last 4 residues of the usually insoluble Tpgamma41-59. To permit a tryptic split this required a change of residue gamma 55 Met to Lys or Arg. The other new Tp contained arginine and was in the position expected for a Ty gamma41-55 (55 Arg). As the material was limited it could not be analysed. When after more than 6 years no example of Hb F Kingston had become available it was decided to describe the variant on the basis of the present evidence. (AU)
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Base de dados:
MedCarib
Assunto principal:
Hemoglobina Fetal
/
Hemoglobinas Anormais
Limite:
Feminino
/
Humanos
/
Lactente
Idioma:
Inglês
Revista:
FEBS lett
Ano de publicação:
1982
Tipo de documento:
Artigo