Association of Dyslipidemia and Androgenetic Alopecia: A Case Control Study

ABSTRACT

Introduction: The association between androgenetic alopeciaand metabolic sydrome has been studied in past with variableresults. In the present study we evaluate the association ofandrogenetic alopecia with dyslipidemia.Material and methods: A prospective hospital based casecontrol study including 100 newly clinically diagnosed malepatients of androgenetic alopecia and age and sex matchedcontrol group was conducted for a period of one year. Lipidprofile including total cholesterol (TC), triglyceride (TG),high density lipoprotein (HDL), low density lipoproteins(LDL) were measured and compared in both the groups.Results: Of the 100 male AGA patients (age range 21-50,mean 34.49), 36 had grade II AGA, 24 had grade III AGA, 20had grade IV AGA, 15 had grade V AGA and 5 had grade VIAGA. Among AGA patients, 60 patients had mild-moderateAGA and 40 patients had severe AGA. Dyslipidemia wasfound to be statistically significantly more common inAGA patients as compared to the control group. The studyalso observed that deranged lipid profile was statisticallysignificantly more common in patients with severe AGA ascompared to patients with mild- moderate AGA.Conclusion: In the present study, dyslipidemia was foundto be more common in patients of androgenetic alopeciaas compared to controls and more common in those withsevere grades suggesting that androgenetic alopecia patientsespecially with severe grades are at higher risk of developingderanged serum lipids and should thus be evaluated fordyslipidemia and other cardiovascular co morbidities.