Clinical, angiographic, and procedural correlates of acute, subacute, and late absorb scaffold thrombosis
JACC Cardiovasc Interv
; 10(18): 1809-1815, 2017. graf, tab
Artigo
em Inglês
| Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP
| ID: biblio-1064020
Biblioteca responsável:
BR79.1
Localização: BR79.1
ABSTRACT
OBJECTIVES:
The authors sought to identify and verify independent correlates of device thrombosis from an analysis of multicenter trials and registries.BACKGROUND:
Recent analyses suggest an increased risk of device thrombosis with Absorb bioresorbable vascular scaffold (Abbott Vascular, Santa Clara, California) implantation compared with metallic drug-eluting stents, and data from moderate size studies suggest a risk relationship to vessel size and technique.METHODS:
From 8,771 consecutively treated patients, 105 patients (1.2%) were identified with scaffold thrombosis within 1 year of implantation. They were matched 21 with controls selected randomly from nonthrombosis patients. Data-restricted multiple logistic analysis was used to identify significant independent covariates of the outcome.RESULTS:
Early (within 1 month) scaffold thrombosis occurred in 69 patients and late (1 to 12 months) thrombosis occurred in 36 patients. Modelling found significant correlations of thrombosis to be final minimal lumen diameter 1.11 balloon/scaffold ratio (OR 2.3; p = 0.022), and reference vessel diameter <2.40 mm (OR 2.1; p = 0.036).CONCLUSIONS:
Suboptimal vessel sizing, procedural technique, angiographic outcomes, and dual antiplatelet therapy discontinuation appear to be the principal determinants of Absorb scaffold thrombosis risk through 12 months after implantation.
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Brasil
Base de dados:
Sec. Est. Saúde SP
/
SESSP-IDPCPROD
Assunto principal:
Trombose
/
Vasos Sanguíneos
/
Stents Farmacológicos
Tipo de estudo:
Ensaio clínico controlado
Idioma:
Inglês
Revista:
JACC Cardiovasc Interv
Ano de publicação:
2017
Tipo de documento:
Artigo
Instituição/País de afiliação:
Azienda Ospedaliera S. Croce e Carle/IT
/
Chinese Academy of Medical Sciences/CN
/
Cleveland Clinic/US
/
Columbia University Medical Center, New York-Presbyterian Hospital/US
/
Department of Cardiology, IRCCS Policlinico San Donato/IT
/
Department of Cardiovascular Medicine at Kyoto University/JP
/
Division of Cardiology, Spaziani Hospital/IT
/
Erasmus MC Rotterdam, Zuid Holland/NL
/
Fatebenefratelli/IT
/
Ferrarotto Hospital-University of Catania/IT