Transfemoral TAVI using the self-expanding ACURATE neo prosthesis: one-year outcomes of the multicentre CE-approval cohort
EuroIntervention
; 13(9): 1040-1046, 2017. graf, tab
Artigo
em Inglês
| Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP
| ID: biblio-1062709
Biblioteca responsável:
BR79.1
Localização: BR79.1
ABSTRACT
Aims:
The aim of this study was to assess the safety and performance of the ACURATE neo transcatheter heart valve and its transfemoral delivery system.Methods andresults:
The prospective, multicentre CE-approval cohort consists of a prospective series of the first 89 patients implanted with the ACURATE neo prosthesis. The primary endpoint was all-cause mortality at 30 days. Mean patient age was 83.7±4.4 years and logistic EuroSCORE I was 26.5±7.7%.Procedural success was obtained in 84 patients (94.4%). At 30 days, three patients had died, and two major strokes and one reintervention for a ventricular septal defect occurred, leading to a major adverse cardiac and cerebrovascular event (MACCE) rate of 6.7%. Eight patients (10.3%) received a permanent pacemaker.At one year, 20 patients (22.5%) had died and the MACCE rate was 27%. Effective orifice area was 1.76±0.34 cm2, and mean gradient 7.5±2.8 mmHg. Only three patients (4.5%) had moderate paravalvular regurgitation. NYHA Class III/IV was present in 94.4% of patients at baseline, in 9.9% at 30 days and in 4.5% at one year post procedure.Conclusions:
This first-in-human experience with a novel self-expanding heart valve showed low rates of procedural mortality, major stroke and pacemaker implantation, and good performance outcomes.
Buscar no Google
Coleções:
Bases de dados nacionais
/
Brasil
Contexto em Saúde:
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Doença Cardiovascular
Base de dados:
Sec. Est. Saúde SP
/
SESSP-IDPCPROD
Assunto principal:
Estenose da Valva Aórtica
/
Morte
Idioma:
Inglês
Revista:
EuroIntervention
Ano de publicação:
2017
Tipo de documento:
Artigo
Instituição/País de afiliação:
German Heart Center/DE
/
Instituto Dante Pazzanese de Cardiologia/BR
/
Kerckhoff Heart and Lung Center/DE
/
Osaka University Graduate School of Medicine/JP
/
University Heart Center Hamburg/DE
/
University Hospital Bonn/DE
/
University Hospital Cologne/DE