Influence of age and coronary artery disease on homocysteine levels in the young old compared with the old old and the oldest old
Am J Geriatr Cardiol
; 15(03): 165-173, 2006. tab
Artigo
em Inglês
| Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP
| ID: biblio-1059449
Biblioteca responsável:
BR79.1
Localização: Br79.1
ABSTRACT
A total of 172 elderly individuals, divided into case and control groups based on the diagnosis of coronary artery disease, underwent coronary angiography to investigate the influence of age and coronary artery disease on homocysteine levels. The subjects were divided into three age ranges 6574 years, 7579 years, and 80 years and older. Continuous homocysteinemia was associated with a risk ratio for coronary artery disease of 1.07 for each ìmol/L increase in homocysteine level. Hyperhomocysteinemia (values above 14 ìmol/L) constituted an independent risk factor for coronary artery disease, with a risk ratio of 2.03. There was a progression of homocysteine levels between the young old and the oldest old only among the case group elderly. There was no difference among the control group elderly. There were no significant differences in vitamin levels. The rise in homocysteine levels from the young old to the oldest old may be considered not a normal pattern, but rather a pattern associated with coronary artery disease. (AJGC. 2006;15165173)
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Coleções:
Bases de dados nacionais
/
Brasil
Base de dados:
Sec. Est. Saúde SP
/
SESSP-IDPCPROD
Assunto principal:
Doença da Artéria Coronariana
/
Angiografia Coronária
/
Homocisteína
Tipo de estudo:
Fatores de risco
Limite:
Idoso
/
Idoso, 80 anos ou mais
/
Humanos
Idioma:
Inglês
Revista:
Am J Geriatr Cardiol
Ano de publicação:
2006
Tipo de documento:
Artigo
Instituição/País de afiliação:
Instituto Dante Pazzanese de Cardiologia/BR