Usefulness of preoperative CA 125 level in decision making of lymphadenectomy in endometrial cancer patients / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
; : 2877-2887, 2005.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-150620
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
The purpose of this study was to evaluate whether the preoperative serum level of CA 125 in patients with endometrial cancer could provide an additional information on determining the extent of surgical staging and which cutoff value might be optimal in this respect.METHODS:
CA 125 levels were measured in 42 patients with endometrial carcinoma who underwent surgery at our institution between March 2000 and December 2004. Operative and postoperative pathologic findings were then correlated with preoperative CA 125 values. Statistical analysis was performed using Mann-Whitney U test, Kruskal-Wallis test, chi-square test and logistic regression model to evaluate the association of preoperative CA 125 levels with various factors. Receiver operating characteristic (ROC) curve was used to determine which cutoff value of the preoperative CA 125 was optimal.RESULTS:
Univariate analyses showed that elevated CA 125 levels were significantly correlated with an advanced stage, larger tumor size, increasing depth of the myometrial invasion, extrauterine disease, and lymph node metastasis (P30 U/mL whereas lymph node metastasis can be predicted at the CA 125 level of >50 U/mL.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Meta 3.4: Reduzir as mortes prematuras devido doenças não transmissíveis
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Modelos Logísticos
/
Programas de Rastreamento
/
Curva ROC
/
Sensibilidade e Especificidade
/
Neoplasias do Endométrio
/
Tomada de Decisões
/
Excisão de Linfonodo
/
Linfonodos
/
Metástase Neoplásica
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
/
Fatores de risco
/
Estudo de rastreamento
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Obstetrics and Gynecology
Ano de publicação:
2005
Tipo de documento:
Artigo