Clinical Effect of Glutathione (Tathion) on Melasma / 대한피부과학회지
Korean Journal of Dermatology
; : 57-61, 1977.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-190627
Biblioteca responsável:
WPRO
ABSTRACT
Tatbion is a tripeptide, reduced form of Glutathione(GSH or p-glutamyl-cysteiny1 -glycine). Glutathione(SH compound)is believed to inhibit melanin formation by combining witb the copper in tyrnsinase whicb is essential in the conversion of tyrosine to DOPA (3, 4-dihydroxyphenylalanine) and DOPA to DOPA-quinone or by forming cornplex with the intermediate in the tyrosine-to-melaa.in reaction. The effect of Tathion in the treatment of melasma has not been reported in Korea. We have observed the effect of Tatbion in 150 patients with melasma. After the average duration of Gwks of treatment(50-100mg tree tirnes/daily), we were abIe to grade the results as follow. Excellent(Pigmentation almost disappeared) 17. 4 % Good (Pigmentation markedly improved) 56. 7% Fair (Pigmentation slightly improved 7. 3% None (No effect) 18.6% The result showed relatively good effects of Tathion in the treatment of 122pts (81.4%) with melasma in total. The brief review of literature on the treatment of melasma was undertaken.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tirosina
/
Di-Hidroxifenilalanina
/
Cobre
/
Glutationa
/
Coreia (Geográfico)
/
Melaninas
/
Melanose
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Ano de publicação:
1977
Tipo de documento:
Artigo