A way out or a new prospect: The future development of autologons hematopoietic stem cell transplantation in type 1 diabetes therapy / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12): 445-447, 2012.
Article
em Zh
| WPRIM
| ID: wpr-427274
Biblioteca responsável:
WPRO
ABSTRACT
The direetion of radical treatment ( complete remission ) for type 1A diabetes is to correct immune disorder and to full repair damaged pancreatic islet cells.It includes the application of immune modulators and islet β-cell replacement therapy.Autologous hematopoietic stem cell transplantation (AHSCT) is a new promising approach for the treatment of type 1A diabetes by reconstitution of immunotolerance and promoting β-cell regeneration.The candidates for AHSCT are limited to the people with early-onset diabetes and keeping obvious residual islet β-cell function.Because of the potential mechanisms underlying the action of AHSCT is still not very clear,careful balancing of the pros and coins of A HSCT is still needed by further trials and intensive studies.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Endocrinology and Metabolism
Ano de publicação:
2012
Tipo de documento:
Article