Up-regulation of Expression of Phosphatidylinositol 3-kinase in Psoriatic Lesions / 中华皮肤科杂志
Chinese Journal of Dermatology
; (12)1994.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-518978
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the correlation between phosphatidylinositol 3 kinase (PI3-kinase) and the pathogenesis of psoriasis. Methods By dot hybridization, in situ hybridization and immunohistochemistry, expression of PI3 kinase was observed in twelve psoriatic and five normal epidermis. Results In psoriatic epidermis, expression of PI3 kinase gene and protein was elevated obviously compared with that of normal skin. Conclusion PI3 kinase may be closely associated with hyperproliferation of psoriatic keratinocytes.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Dermatology
Ano de publicação:
1994
Tipo de documento:
Artigo