Cost-effectiveness Analysis of Three Sulfonylureas in Treatment of Noninsulin Dependent Diabetes Mellitus / 中国药房

ABSTRACT

OBJECTIVE:To compare the therapeutic effects and costs among glimepiride,glipizide and gliclazide on patients with noninsulin dependent diabetes mellitus METHODS:85 patients were randomized into three groupsgroup A received glimepiride,group B received glipizide and group C received gliclazide Pharmacoeconomic evaluation was performed by minimized cost analysis:RESULTS:The effective rates of group A,group B and group C were 85 71%,86 21% and 85 71%,respectively The adverse reaction rates were 7 14%,6 90% and 10 71%,and the expenditures 682 64 yuans,436 24 yuans and 464 34 yuans,respectively CONCLUSION:By cost-effectiveness analysis,glipizide is best one among three sulfonylureas