The Effect of Hyperglycemia on the Prognosis of Acute Lymphocytic Leukemia during Induction Chemotherapy / 中国医师杂志
Journal of Chinese Physician
; (12)2001.
Article
em Zh
| WPRIM
| ID: wpr-524165
Biblioteca responsável:
WPRO
ABSTRACT
Objective To explore the effect of hyperglycemia on the survival time, duration of disease remission and complications during induction chemotherapy for acute lymphocytic leukemia(ALL). Methods The treatment-related complications in 98 adult ALL patients with or without hyperglycemia were retrospectively analyzed. Survival time and complete remission duration(CRD) were evaluated using Kaplan-Meier method. Cox regression analysis was used to examine whether hyperglycemia was an independent predictor of disease recurrence and death. Results ALL patients with hyperglycemia were found to be older, and more likely to occur thrombocytopenia. ALL patients with hyperglycemia had a shorter CRD and survival time, and were more likely to develop infection and neuropathy. Conclusion Hyperglycemia during induction chemotherapy for ALL increased the frequency of infection and the risk of disease recurrence and death.
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1
Base de dados:
WPRIM
Tipo de estudo:
Prognostic_studies
Idioma:
Zh
Revista:
Journal of Chinese Physician
Ano de publicação:
2001
Tipo de documento:
Article