Three-dimensional conformal radiotherapy for brain gliomas / 中国癌症杂志

ABSTRACT

Purpose:To study the effects and efficacy of three-dimensional conformal radiotherapy (3-DCRT) for brain gliomas. Methods:Thirty cases of brain gliomas were treated by three-dimensional conformal radiotherapy.Of these 21 patients had nesidual tumor after operation, 5 were post-operative recurrent patients and 4 were post-radiotherapy recurrent patients.The total irradiation dose was 42 Gy(BED 56 Gy). All patients received 6 Gy/F.qod.Results:In the 1-3 months after 3-DCRT,the results examined by CT or MRI showed that in the 30 patients,these were CR 40.0%,PR (33.3%), NC 20.0%, PD 6.7%,The total response rate was (CR+PR) 73.3%.No acute or chronic radiation side effects were observed in the follow up .The 0.5-,1-,2-,3-year survival rates were 93.3%,77.8%,71.31%,53.18% respectively.Conclusions:The result shows that 3-DCRT of brain gliomas can improve therapeutic effect.