Effect of gypenosides on hepatic function and fibrosis in rats with immune fibrosis / 第二军医大学学报
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-554557
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To study the effect of gypenosides (GPs) on the hepatic function and fibrosis progression in Wistar rats with immune fibrosis.Methods:
The model of immune fibrosis was established by injection of human albumin. Rats in treated group were also administered with 0. 5 mg GPs during 30 d human albumin attack. The hepatic function of rats was e-valuated by determining the levels of ALT, TBIL and TBA in serum. The progression of hepatic fibrosis was evaluated by the levels of HA, PC Ⅲ and LN by radioimmunoassay (RIA) and confirmed by rats tissue pathology analysis.Results:
Albumin injection significantly elevated the levels ALT, TBIL, TBA, HA, PCⅢ(P
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Academic Journal of Second Military Medical University
Ano de publicação:
1999
Tipo de documento:
Artigo