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Effect of gypenosides on hepatic function and fibrosis in rats with immune fibrosis / 第二军医大学学报
Article em Zh | WPRIM | ID: wpr-554557
Biblioteca responsável: WPRO
ABSTRACT
Objective:To study the effect of gypenosides (GPs) on the hepatic function and fibrosis progression in Wistar rats with immune fibrosis. Methods: The model of immune fibrosis was established by injection of human albumin. Rats in treated group were also administered with 0. 5 mg GPs during 30 d human albumin attack. The hepatic function of rats was e-valuated by determining the levels of ALT, TBIL and TBA in serum. The progression of hepatic fibrosis was evaluated by the levels of HA, PC Ⅲ and LN by radioimmunoassay (RIA) and confirmed by rats tissue pathology analysis. Results: Albumin injection significantly elevated the levels ALT, TBIL, TBA, HA, PCⅢ(P
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Texto completo: 1 Base de dados: WPRIM Idioma: Zh Revista: Academic Journal of Second Military Medical University Ano de publicação: 1999 Tipo de documento: Article
Texto completo: 1 Base de dados: WPRIM Idioma: Zh Revista: Academic Journal of Second Military Medical University Ano de publicação: 1999 Tipo de documento: Article