Thiazolidinediones combined with metformin in treatment of polycystic ovary syndrome:a systematic review / 第二军医大学学报
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-567420
Biblioteca responsável:
WPRO
ABSTRACT
Objective To assess the efficacy and safety of thiazolidinediones combined with metformin in treatment of polycystic ovary syndrome.Methods Electronic database searching was performed on Medline,Cochrane Library,EMbase,EBSCO,ScienceDirect,OVID,Springer LINK,Wiley,Chinese biology and medicine(CBM),China National Knowledge Infrastructure(CNKI),and Chongqing VIP Database;meanwhile,unpubished literature,conference papers and dissertations were also searched manually.The data included those from the establishment to November 2009.Randomized or clinical controlled trials concerning the thiazolidinediones and metformin combination therapy for PCOS were selected and assessed for the methodological quality,and Meta-analysis was performed using statistical software Revman 5.0.Results Five randomized controlled trials met the inclusion criteria and were included.Compared to metformin group,thiazolidinediones combined with metformin significantly improved insulin resistance(P
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Ensaio clínico controlado
/
Revisão sistemática
Idioma:
Chinês
Revista:
Academic Journal of Second Military Medical University
Ano de publicação:
1981
Tipo de documento:
Artigo