An tentative radiological and basical studies of preventing the constriction after the laminectomy by using the nano-hydroxyapatite/polyamide-66 composite material artificial vertebral lamina / 重庆医科大学学报

ABSTRACT

Objective: To discuss the radiological evaluation after the experiment implanted artificial vertebral lamina made from n-HA/PA66 into the defect of vertebral lamina,in order to evaluate its value in preventing the complication of postlaminectomy.Methods:22 male dogs aged one year were classified randomly into three groups the experimental group(13 dogs)and the control group(9 dogs).The specimens were examined by the methods of plain roentgenography,MRI and histology.Results:The X-ray in the experimental group,it was becoming cloudy around the operative area in the 8th week;till 24th week,the density of the operative area was the same with the density of bone.The histology in the experimental group,from the 8th week,there were many cartilage cells and lamellar bone observed.While in the control group,it was just fibrous layer forming.MRIthe reconstructed segment after the laminoplasty was detected clearly by MRI,which coincided with the histology.Compared with the control segment,the numbers of the area of vertebral canal and the sagital axis were significantly different(P