Effect of quercetin on expression of TGF-?_1 in kidney of streptozotocin-induced diabetic rats / 中国糖尿病杂志
Chinese Journal of Diabetes
; (12)1994.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-582028
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the mechanism of Quercetin treatment on diabetic nephropathy.Methods Quercetin 100mg/(kg?d) was given to diabetic rats.Urinary albumin excretion was measured by radioimmunoassay.The expression of TGF ? 1 protein and TGF ? 1 mRNA in renal cortex of diabetic rats were determined by immunohistochemical staining and RT PCR analysis.Results Quercetin treatment decreased urinary albumin excretion in diabetic rats.TGF ? 1 immunohistochemical staining and TGF ? 1 mRNA levels in Quercetion treated group was significantly decreased than untreated DM group ( P
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Diabetes
Ano de publicação:
1994
Tipo de documento:
Artigo