Effect of quercetin on hemoglobin and blood biochemical indexes in rats following exhausted exercise / 中国组织工程研究

ABSTRACT

Totally 40 male SD rats were randomly divided into sedentary group (G1, n =8), exercise group (G2, n =16) and exercise with drug group (G3, n =16). Animal models were established by treadmill training. At the last time for training, rats in the G2 and G3 were separately divided into control group (n =8) and exhausting exercise group (n =8). Rats in the G3 were orally injected with quercetin 50 mg/kg by intragastric administration everyday at 3 hours before training, and others in the G1 and G2 were fed with the same amount of saline by gavage. Hemoglobin (Hb) content, activities of serum lactate dehydrogenase (LDH), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were determined in exhausted rats. The results showed that quercetin could remarkably restrain the decrease of Hb content and the increase of activities of ALT, AST and LDH after exhausted exercise.