Inhibition of the crude extract of Eriobotryae Folium collected from different districts towards phosphodiesterase-4 / 药物评价研究
Drug Evaluation Research
; (6): 769-772, 2017.
Article
em Zh
| WPRIM
| ID: wpr-619574
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the inhibition of Eriobotryae Folium from twenty different districts towards phosphodiesterase 4(PDF4) in vitro.Methods The Eriobotryae Folium were extracted with 95% ethanol reflux and the inhibition rates against PDE4D2 were carried out by liquid scintillation counting method.Results All the samples exhibited inhibitory activities towards PDE4 at 5 mg/L.Among them,nine samples were of the inhibition rate less than 80%,eleven samples were of more than 80% inhibition and eight samples were of more than 90% inhibition.Conclusion The Eriobotryae Folium shows significantly different inhibitory activities towards PED4.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Drug Evaluation Research
Ano de publicação:
2017
Tipo de documento:
Article